![]() ![]() ![]() Decreases of MPV after adenoidectomy and adenotonsillectomy were observed, but only the effect of adenotonsillectomy had a statistical significance (total SMD = − 0.72 95% CI = − 1.18 – -0.26, P < 0.05). A significant decrease of MPV was found in pediatric SDB patients who underwent surgery (total SMD = − 0.36 95% CI = − 0.70– -0.02, P < 0.05). Total standardized mean difference (SMD) in MPV between pediatric SDB and non-SDB was 0.51 (95% CI =0.30–0.72, P < 0.05). Six of them including 963 subjects showed that a significant increase of MPV was noted in pediatric SDB compared to those in pediatric non-SDB ( P < 0.05). There were seven studies included in the review. Meta-analysis was used to compare the change of MPV in pediatric SDB, and sub-group analysis was also used to compare the MPV decrease after surgeries of adenoidectomy or adenotonsillectomy. MethodsĪ systemic review of the studies from PubMed, EMBASE, and Cochrane Library databases was conducted in March 2020, supported by reviewing of published articles for studies comparing MPV in pediatric SDB. ![]() The aim of this study was to perform systematic review and meta-analysis to investigate the difference on MPV values for pediatric SDB, and compare the change on MPV after surgery in patients with pediatric SDB. Increase of MPV level may cause failure to thrive or increased upper airway infection rate. Mean platelet volume (MPV) was an inflammatory marker, related to increased inflammatory condition of pediatric patients. Pediatric sleep-disordered breathing (SDB) correlated with respiratory conditions of snoring and hypopnea. ![]()
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